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Showing posts from April, 2018

Colon Xenograft Models and Cancer Research Tools by Altogen Biosystems

Altogen Biosystems is a recognized producer and custom research organization for the pharmaceutical industry. Custom research products and other goods include xenografts, optimization of preclinical research, stable transfection of cells, IND applications and more. Dedicated to assisting researchers with state-of-the-art and efficient services, Altogen Biosystems endeavors to further modern clinical techniques. Visit the Altogen Biosystems website for colon xenograft models .

Colon Cancer Drug Development with Caco-2 Cells

Initially derived from human tissue by Jorgen Fogh, Caco-2 cells are human colorectal adenocarcinoma cells that can serve as transfection hosts, provided that the transfection is done with minimally-intrusive transfection reagents . The cells exhibit in vivo  characteristics even in vitro , such as the differentiation into enterocytes that are found in the small intestine. Caco-2 cells produce the correct proteins and enzymes that are found in real tissue, making them optimal candidates for initial drug research and the monitoring of cell physiology after introduced foreign DNA or other nucleic acid sequence.