The Caco-2 cell line was taken from the colon cells of a 72-year-old Caucasian male who had colorectal adenocarcinoma. Caco-2 cells have epithelial morphological characteristics and exhibit adherent cultural properties. Caco-2 cells are suitable transfection hosts, and a Caco-2 Transfection Reagent to transfect Caco-2 cells can be purchased from Altogen Biosystems for the study of colon cancer. The Caco-2 cell line is known to differentiate rapidly and be vulnerable to human immunodeficiency virus 1. Caco-2 products include keratin, retinol binding protein 2, and retinoic acid binding protein 1.
Tumorigenic colon cancer cells cultured from a 72 year old Caucasian male patient with colorectal adenocarcinoma were used to develop the Caco-2 HTB-37 cell line. The Caco-2 cells are known to double in about 62 hours and have been characterized as tumorigenic, epithelial cells.The use of these cells as transfection models for human colon cancer research is faciliated by the use of Caco-2 transfection reagents created by Altogen Biosystems . The Caco-2 transfection reagent is a biodegradable polymer based reagent that yields high transfection efficacy while also being gentle enough to be used to analyze an individual cell. Caco-2 Transfection Reagent (Colon Carcinoma Cells)
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